Neonatal Candidiasis treatment

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Treatment tips

  • Empirical antifungal therapy should be considered in high-risk infants once Candida infection is suspected.
  • Central venous and arterial catheters should be removed.
  • Temporary, peripheral access should be used for several days while the patient is receiving antifungal therapy until documentation of negative blood cultures.

Medical treatment

  • Fluconazole : 12 mg/kg/day (25 mg/kg loading dose)
  • Amphotericin B deoxycholate: 1 mg/kg/day
  • Liposomal amphotericin B : 5 mg/kg/day (if urine cultures are negative).
  • Micafungin: 10 mg/kg/day (if eye involvement is excluded).


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