Neonatal HSV infection treatment

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Measures of prevention

  • Avoid unprotected genital and oral sexual contact during late
    pregnancy or to take suppressive therapy with an oral antiviral medication.
  • Suppressive antiviral is recommended from 36 weeks of gestation in HSV-2 seropositive women at high risk for an active HSV outbreak at the time of labor.
  • Antiviral treatment for pregnant females with an active primary or recurrent genital outbreak near or at the time of delivery.
  • Occlusive coverage on non genital HSV lesions before vaginal delivery helps to prevent infection .
  • Cesarean delivery is recommended when a mother experiences primary genital herpes or symptomatic outbreaks near or at the time of delivery.
  • Prophylactic acyclovir should be considered for the neonate if active primary herpes infection was in the mother at the time of delivery

Medical treatment

For herpetic skin lesions :

  • Acyclovir(early) : 30 mg/kg/day.

For disseminated and CNS disease:

  • Acyclovir : 20 mg/kg iv every 8 hours for 21 days.

For skin and mucous membranes affection:

  • Acyclovir : 20 mg/kg iv every 8 hours for 14 days.

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