Isotretinoin side effects checklist Dermatology Games 3 weeks ago 1. Whole Skin Changes Dry skin Skin fragility Erythema (skin redness) Increased susceptibility to sunburn Decreased sweating Dryness of mucosal tissues Hair changes (e.g., thinning, brittle hair) Hand changes (e.g., dryness, cracking) Skin atrophy Acne flare-ups 2. Ophthalmic Changes Dry or irritated eyes Eye pain Vision changes Conjunctival changes (irritation or redness in the eyes) 3. Nasopharyngeal Changes Dry nose Nasopharyngitis (inflammation of the nose and throat) Upper respiratory tract infections (URTI) Epistaxis (nosebleeds) Cough 4. Oral Changes Dry lips Cheilitis (inflammation or cracking of the lips) Dry and sore mouth Excessive thirst 5. Mood and Neurological Changes Hearing changes Headache Mood changes (e.g., irritability, depression) Decreased appetite Increased appetite Fatigue 6. Musculoskeletal Changes Back pain Arthralgia (joint pain) Musculoskeletal discomfort 7. Gastrointestinal Changes Gastrointestinal disorders (e.g., indigestion, diarrhea) Abdominal pain 8. Infections Infections (e.g., bacterial or viral) Fever (link to isotretinoin is unclear) 9. Other Adverse Effects Stevens-Johnson syndrome (rare, severe skin reaction) Morbilliform eruption (measles-like rash) Pyogenic granuloma (benign vascular lesion) Irregular menstrual cycle 10. Laboratory Abnormalities Altered liver function tests Abnormal lipid profiles (e.g., elevated cholesterol, triglycerides) Elevated erythrocyte sedimentation rate (ESR) Proteinuria (presence of protein in urine) Abnormal specific gravity in urine tests Abnormal kidney function tests Altered glucose levels Changes in calcium-phosphate regulation Abnormal sperms’ morphology See more