How erythema annulare centrifugum is treated?

General tips to treat erythema annulare centrifugum

• There is no defenitive treatment of erythema annulare centrifugum.
• Identify and treat the underlying condition if present.
• The skin lesions will usually improve, if the underlying condition has been successfully treated.
• Dermatophytosis is the most common reported associated skin infection, so careful examination of the skin is important. The feet, groin, and nails have to be examined.
• If no underlying condition is identified, treatment is mainly asymptomatic.
• In most cases no causative trigger can be detected, and the treatment is empiric and asymptomatic.

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Treatment options of erythema annulare centrifugum

Topical treatment

• Topical cortsteroids
  • Topical corticosteroids applied to the advancing border of the lesions
• Topical calcipotriol
  • once daily.
• Topical tacrolimus
  • Topical tacrolimus 0.1% ointment twice daily.
• Topical antipruritics
  • lotions containing menthol, camphor, or pramoxine.

Systemic treatment

• Systemic steroids
  • Recurrence is common.
• Sedating antihistamines
• Antibiotics
  • Azithromycin : 250 mg once daily until clinical improvement or maximum of three weeks.
  • Erythromycin stearate : (1000 mg per day) for 2 weeks.
  • Metronidazole : (400 mg per day) for six weeks.
• Phototherpay
  • Natural sunlight exposure.
  • NB-UVB
    • start at 0.25 J/cm² and increased in 20% increments.
• Other options
  • Etanercept 25 mg twice weekly injections.
  • Apremilast : 30 mg twice daily

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